Mechanochemical synthesis evaluation of nanocrystalline bone-derived bioceramic powder using for bone tissue engineering

Development of Collagen/Demineralized Bone Powder Scaffolds and Periosteum-Derived Cells for Bone Tissue Engineering Application

The aim of this study was to investigate physical and biological properties of collagen (COL) and demineralized bone powder (DBP) scaffolds for bone tissue engineering. DBP was prepared and divided into three groups, based on various particle sizes: 75-125 µm, 125-250 µm, and 250-500 µm. DBP was homogeneously mixed with type I collagen and three-dimensional scaffolds were constructed, applying ...

Biodegradable Polymer-bioceramic Composite Scaffolds for Bone Tissue Engineering

Critical size bone defects due to trauma or disease are very difficult to repair via the natural growth of the host bone. Therefore, these defects must be filled with a bridging material (scaffold), which should also, in combination with relevant cells and signalling molecules, promote the regeneration of new bone tissue. In this context, bone regeneration is one of the most attractive areas in...

Sol-gel synthesis of (Ca-Ba)TiO3 nanoparticles for bone tissue engineering

Piezoelectric materials are the group of smart materials which have been recently developed for biomedical applications, such as bone tissue engineering. These materials could provide electrical signals with no external source power making them effective for bone remodeling. Between various types of materials, BaTiO3 and CaTiO3 are nontoxic piezoelectric ceramics, which recently have been intro...

Poly(lactic acid) (PLA) Nanofibers for Bone Tissue Engineering

Aligned and random nanofibrous nanocomposite scaffolds for bone tissue engineering

Aligned and random nanocomposite nanofibrous scaffolds were electrospun from polycaprolactone (PCL), poly (vinyl alcohol) (PVA) and hydroxyapatite nanoparticles (nHA). The morphology and mechanical characteristics of the nanofibers were evaluated using scanning electron microscopy and tensile testing, respectively. Scanning electron microscopy revealed fibers with an average diameter of 123 ± 3...